Survival Impact of an On-Site Medicalization Program in the Control of COVID-19 Outbreaks in 11 Nursing Homes.

Background: The elderly admitted to nursing homes have especially suffered the havoc of the COVID-19 pandemic since most of them are not prepared to face such health problems.

Methods: An innovative coordinated on-site medicalization program (MP) in response to a sizeable COVID-19 outbreak in three consecutive waves was deployed, sharing coordination and resources among primary care, the referral hospital, and the eleven residences. The objectives were providing the best possible medical care to residents in their environment, avoiding dehumanization and loneliness of hospital admission, and reducing the saturation of hospitals and the risk of spreading the infection.

Distance Correlation-Based Feature Selection in Random Forest.

The Pearson correlation coefficient (ρ) is a commonly used measure of correlation, but it has limitations as it only measures the linear relationship between two numerical variables. The distance correlation measures all types of dependencies between random vectors and in arbitrary dimensions, not just the linear ones. In this paper, we propose a filter method that utilizes distance correlation as a criterion for feature selection in Random Forest regression.

Tunable multilayered lens made of PDMS with a biconical surface profile design and manufacture.

A polymer that has been used for the development of optical components and has had a significant impact is polydimethylsiloxane (PDMS) due to its remarkable mechanical and optical properties and easy handling. We present a practical and straightforward technique for designing and manufacturing a tunable graded index, graphical input (GRIN)-type lenses, and tunable lenses with a homogeneous refractive index made of PDMS. Implementing a biconical surface profile in a tunable plane-convex lens is proposed for elaborating both a homogeneous refractive index lens and a multilayered GRIN-type lens with a constant increased variation of 0.

Membrane interactions of Ocellatins. Where do antimicrobial gaps stem from?

The antimicrobial peptides Ocellatin-LB1, -LB2 and -F1, isolated from frogs, are identical from residue 1 to 22, which correspond to the -LB1 sequence, whereas -LB2 carries an extra N and -F1 additional NKL residues at their C-termini. Despite the similar sequences, previous investigations showed different spectra of activities and biophysical investigations indicated a direct correlation between both membrane-disruptive properties and activities, i.e.

Mapping the Cerebellar Cognitive Affective Syndrome in Patients with Chronic Cerebellar Strokes.

The cerebellar cognitive affective syndrome (CCAS) has been consistently described in patients with acute/subacute cerebellar injuries. However, studies with chronic patients have had controversial findings that have not been explored with new cerebellar-target tests, such as the CCAS scale (CCAS-S). The objective of this research is to prove and contrast the usefulness of the CCAS-S and the Montreal Cognitive Assessment (MoCA) test to evaluate cognitive/affective impairments in patients with chronic acquired cerebellar lesions, and to map the cerebellar areas whose lesions correlated with dysfunctions in these tests.