Publications by authors named "J L McPartland"

Individuals with autism spectrum disorder (ASD) tend to experience greater difficulties with social communication and sensory information processing. Of particular interest in ASD biomarker research is the study of visual attention, effectively quantified in eye tracking (ET) experiments. Eye tracking offers a powerful, safe, and feasible platform for gaining insights into attentional processes by measuring moment-by-moment gaze patterns in response to stimuli.

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Autism and social anxiety (SA) share behavioral features like reduced eye contact, variable social attention, and differences in social interactions. However, the impact of the co-occurrence of these conditions (e.g.

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Objective: KeepCalm is a digital mental health application, co-designed with community partners, that incorporates wearable biosensing with support for teams to address challenging behaviors and emotion dysregulation in children on the autism spectrum.

Methods: We followed a user-centered design framework. Before app development, we conducted design workshops, needs assessment interviews, a systematic review, and created an Expert Advisory Board.

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Article Synopsis
  • The study investigates synaptic density in autistic adults using positron emission tomography (PET) and synaptic vesicle glycoprotein 2A (SV2A) as a marker.
  • Results show that autistic individuals exhibit a 17% lower synaptic density across the whole cortex compared to non-autistic peers, with significant deficits in various brain regions, especially the prefrontal cortex.
  • The findings suggest that lower synaptic density is associated with increased autistic features, pointing to a potential molecular basis for autism that requires further exploration.
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In some cases, a clinician's perceptions of a child's autism-related behaviors are not the same as the child's caregiver's perceptions. Identifying how these discrepancies relate to the characteristics of the child is critical for ensuring that diagnosis procedures are unbiased and suitable for all children. This study examined whether discrepancies between clinician and caregiver reports of autism features related to the child's sex at birth.

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