The immune response of allophenic mice to the synthetic polymer GL phi. III. Allotype analysis of anti-GL phi antibody.

Allophenic mice produced by aggregating 8-cell embryos from a low responder (CBA) and a high responder (DBA/1) strain to the synthetic amino acid polymer GL phi.. In some strains of mice the immune response to this polymer is controlled by two genes, alpha and beta, which map to the IE/C and IA subregions of the H-2 complex, respectively.