Two-step hot isostatic pressing densification achieved non-porous fully-densified wood with enhanced physical and mechanical properties.

A new two-step densification method for wooden materials entitled hot isostatic pressing (HIP) is proposed. This method has the advantage over previous densification methods that can achieved almost the full densification of wood, reaching values up to 1.47 kg/m, which exceeds any value ever reported for a hardwood species.

Does substance use disorder treatment completion reduce the risk of treatment readmission in Chile?

Background: Recovery from substance use disorders (SUD) often entails multiple treatment episodes, which clashes with a context of a treatment system with limited resources and long waiting. Treatment retention and completion have been pointed out as key elements for sustainable achievement; however, most of the evidence generated focuses on opioids and injected substances, which is hardly transferable to the Latin American context.

Objectives: This study aims to estimate the effect of SUD treatment completion on the risk of being readmitted to a SUD treatment in Chile.

Insights on the Evolutionary Genomics of the Genus: Potential New Species and Genetic Content Among Lineages.

, a genus established in 2008, is a relevantly abundant taxonomic group present in the microbiome of human and other mammalian gastrointestinal (GI) tracts. Several described (or proposed) species are available at this date. However, despite the increasing level of knowledge about , its diversity is still poorly understood.

Synchronous bilateral breast cancer treated with a 3-week hypofractionated radiotherapy schedule: clinical and dosimetric outcomes.

Background And Purpose: Synchronous bilateral breast cancer (SBBC) accounts for 1-3.5% of breast cancer patients. The aim of this study was to evaluate dosimetric issues, clinical outcomes, and acute toxicities for SBBC patients receiving synchronous bilateral hypofractionated radiotherapy (SBHRT) and to compare them with patients treated with synchronous bilateral normofractionated RT schedule (SBNRT).

Transactivation activity and nucleocytoplasmic transport of β-catenin are independently regulated by its C-terminal end.

The key protein in the canonical Wnt pathway is β-catenin, which is phosphorylated both in absence and presence of Wnt signals by different kinases. Upon activation in the cytoplasm, β-catenin can enter into the nucleus to transactivate target gene expression, many of which are cancer-related genes. The mechanism governing β-catenin's nucleocytoplasmic transport has been recently unvealed, although phosphorylation at its C-terminal end and its functional consequences are not completely understood.