Publications by authors named "J L Maggs"
Article Synopsis
- - The study analyzed how the triple therapy drug Elexacaftor/tezacaftor/ivacaftor (ETI) significantly improved the health and lives of people with cystic fibrosis (pwCF), prompting them to reconsider what "being healthy" means beyond just physical health.
- - Using interviews with 91 pwCF and 23 caregivers, researchers identified four key themes related to their experiences on ETI: dramatic health improvements, less mental strain, a focus on overall wellness and managing other conditions, and changes in social and self-identity.
- - The findings suggest that ETI has raised health expectations for pwCF, indicating a need for cystic fibrosis care to adapt by emphasizing overall health management, addressing
Background: As people with cystic fibrosis (PWCF) live longer due to the breakthrough drug elexacaftor-tezacaftor-ivacaftor (ETI), they have questioned whether other CF therapies could be safely discontinued. SIMPLIFY was the first prospective, randomized trial to evaluate non-inferiority of discontinuing versus continuing two therapies. The QUEST (Qualitative Understanding of Experiences in the SIMPLIFY Trial) study was conducted to understand experiences of PWCF enrolled in SIMPLIFY, including why they joined, perceptions of randomization, decision-making around study withdrawal, and considerations for future discontinuation studies.
View Article and Find Full Text PDFPatterns, clusters, and transitions in U.S. state ENDS policy implementation: 2010-2020.
PLOS Glob Public Health
November 2024
Electronic nicotine delivery systems (ENDS), such as e-cigarettes, have become increasingly used across the world. To respond to global public health challenges associated with vaping, governments have implemented numerous ENDS policies. This research highlights the patterns, clustering, and transitions in U.
View Article and Find Full Text PDFArticle Synopsis
- The study examines how family and peer stressors affect alcohol use patterns in Mexican-origin adolescents over time, utilizing longitudinal data from 674 participants.
- Results indicate that early adolescent stressors are more effective as predictors of alcohol use trajectories when analyzed as growth trajectories rather than as individual instances of stress.
- The findings highlight the importance of developing strategies to reduce the long-term impact of stressors on alcohol consumption among Latinx youth.
John Schulenberg as a developmental scholar and mentor: Personal reflections.
J Res Adolesc
December 2024
John Schulenberg has had significant impact on developmental science. His conceptual writing and empirical research, grounded in developmental contextualism, emphasized the critical role that developmental transitions play in shaping health risks, especially substance use, across the life course. Schulenberg's integration of developmental concepts with large-scale epidemiological studies, particularly through his leadership in the Monitoring the Future study, provides key insights into how significant life changes-such as school transitions, employment, and relationships-interact to influence well-being across adolescence and early adulthood.
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