Publications by authors named "J L Lennox"

Article Synopsis
  • In March 2020, the White House Coronavirus Task Force identified the need for expert treatment guidelines for managing COVID-19 due to its life-threatening nature and lack of known effective treatments.
  • The NIH was tasked with quickly assembling a panel of experts to create "living" guidelines, which would be regularly updated as new information about the virus emerged.
  • The article reflects on the Panel's experiences over four years, summarizes its final recommendations, discusses ongoing challenges, and notes that the responsibility for COVID-19 guidelines will now shift to professional organizations following the end of the public health emergency.
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Background: This study was aimed at evaluating the microbial quality and proximate analysis of soymilk produced and sold within Calabar Metropolis.

Methodology: Soymilk samples were purchased in pairs from five locations in Calabar Metropolis. The samples collected were subjected to microbiological and proximate analysis to ascertain the hygienic standards of the products and nutrient contents.

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Article Synopsis
  • * They analyzed data from nearly 5,000 participants prior to starting ART and over 3,000 at 48 weeks on ART, considering factors like age, sex, and genetic similarities to assess variability in CD4 T-cell counts.
  • * Although the polygenic score (PGSlymph) had a minimal impact (<1%) on the variability in CD4 T-cell recovery, it showed some significant associations in individuals of African ancestry, particularly when included in more
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Within geographic regions, the existing data suggest that physical habitat (bark, soil, etc.) is the strongest factor determining agroecosystem microbial community assemblage, followed by geographic location (site), and then management regime (organic, conventional, etc.).

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Long-term consequences of human immunodeficiency virus (HIV) are likely the result of persistent inflammation and immune dysfunction of which cytomegalovirus (CMV) is a known contributor. We leveraged 2 AIDS Clinical Trials Group clinical trials exploring the effects of immune modulators (ruxolitinib and sirolimus) on inflammation in people with HIV on antiretroviral therapy to determine whether these interventions affected CMV shedding at various mucosal sites. Analyzing 635 mucosal samples collected, we found no significant difference in CMV levels across study arms or time points.

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