Publications by authors named "J L Lardizabal"

Article Synopsis
  • Early life adversity (ELA) affects the development of corticolimbic circuitry, leading to increased glutamatergic projections from the basolateral amygdala (BLA) to the prefrontal cortex (PFC), which is linked to anxiety behaviors in adolescence.
  • The study utilized a maternal separation (MS) model to investigate how ELA exposure enhances BLA-driven activity in the PFC and found that MS-exposed adolescents showed increased PFC activity when the BLA was stimulated.
  • Despite initial decreases in anxiety-like behavior during early adolescence post-MA inhibition, the long-term effects of ELA resulted in increased BLA-PFC innervation and anxiety responses later in life, indicating that early BLA activity and receptor changes
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Background: Zambia is among the countries making major progress in limiting cases of the neglected tropical disease lymphatic filariasis on the path to reaching global elimination targets. For this trend to continue, it is essential for strategies and policies targeting the disease in Zambia to be based on the most recent and relevant literature. The scope of research on lymphatic filariasis in the Zambian context is currently poorly understood.

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Objective: Oocyte cryopreservation (OC) has increased in recent years; however, there is a paucity of published data on the use of cryopreserved oocytes and associated outcomes.

Methods: A retrospective review of 748 OC cycles between 2013 and 2022 at a private fertility centre was performed. Outcome parameters for oocyte retrieval cycles were reviewed.

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