Publications by authors named "J L Komisar"
Background: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis has been recognised to present with the syndrome of catatonia. In severe cases dysautonomia is representative of malignant catatonia. The treatment with benzodiazepines (BZDs) and electroconvulsive therapy (ECT) may decrease morbidity and mortality in patients presenting with anti-NMDA receptor encephalitis and catatonia.
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- Alcohol is a significant cause of preventable deaths in the U.S., and this study aimed to evaluate the occurrence of phenobarbital-resistant alcohol withdrawal syndrome (AWS) and its risk factors.
- The study compared two groups of patients who received either a standard or low dose of phenobarbital (PHB) while being treated for AWS, but found no significant difference in the rate of PHB-resistant cases between the two groups.
- The only notable risk factor found for developing PHB-resistant AWS was the total dose of benzodiazepines taken in the 24 hours prior to receiving PHB.