Genomic Analysis of a Pan-Resistant Isolate of , United States 2016.

Unlabelled: Antimicrobial resistance is a threat to public health globally and leads to an estimated 23,000 deaths annually in the United States alone. Here, we report the genomic characterization of an unusual , nonsusceptible to all 26 antibiotics tested, that was isolated from a U.S.

Meningococcal carriage among Georgia and Maryland high school students.

Background: Meningococcal disease incidence in the United States is at an all-time low. In a previous study of Georgia high school students, meningococcal carriage prevalence was 7%. The purpose of this study was to measure the impact of a meningococcal conjugate vaccine on serogroup Y meningococcal carriage and to define the dynamics of carriage in high school students.

Endometrial histopathology in patients with laparoscopic proven salpingitis and HIV-1 infection.

Study Objective: To identify sensitive and specific histological criteria for endometritis in women with laparoscopically-confirmed acute salpingitis.

Methods: Women, age 18-40 years of age presenting with complaints of lower abdominal pain ≤2 weeks and no antibiotics use in past two weeks, were enrolled. They underwent clinical examination, screening for HIV; other sexually transmitted infections plus endometrial biopsy sampling for histopathology.

Diversity of factor H-binding protein in Neisseria meningitidis carriage isolates.

Several meningococcal vaccines under development for prevention of serogroup B disease target the factor H-binding protein (FHbp), an immunogenic lipoprotein expressed on the surface of Neisseria meningitidis. Based upon sequence and phylogenetic analyses, FHbp can be classified into 3 protein variants (1, 2 or 3) or 2 subfamilies (A or B). The potential effect of FHbp-containing vaccines on meningococcal carriage is not known.