Publications by authors named "J L Huie"
Effective team science requires procedural harmonization for rigor and reproducibility. Multicenter studies across experimental modalities (domains) can help accelerate translation. The Translational Outcomes Project in NeuroTrauma (TOP-NT) is a pre-clinical traumatic brain injury (TBI) consortium charged with establishing and validating noninvasive TBI assessment tools through team science.
View Article and Find Full Text PDFData interoperability is crucial for effectively combining data for scientific inquiry. To facilitate interoperability, data standards such as a common definition of variables are often developed. The Open Data Commons for Spinal Cord Injury (odc-sci.
View Article and Find Full Text PDFBackground: Contemporary surgical practices for traumatic brain injury (TBI) remain unclear. We describe the clinical profile of an 18-centre US TBI cohort with cranial surgery.
Methods: The prospective, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (2014-2018; ClinicalTrials.
Article Synopsis
- - The complex nature of spinal cord injury (SCI) creates challenges for translating research into practical treatments, leading to a need for advanced data science solutions to manage diverse injury data and outcomes.
- - To address privacy concerns with sensitive data, a Private Data Commons for SCI (PDC-SCI) has been developed, enabling secure, organized data sharing among researchers for collaborative studies.
- - An example of PDC-SCI in action is demonstrated through the VA Gordon Mansfield SCI Consortium, which integrates various data types to enhance research insights and knowledge discovery in SCI.
Article Synopsis
- - The study aimed to compare the motor examinations done by the clinical neurosurgery team with the ISNCSCI assessments, since the latter can be time-consuming and impractical during acute spinal cord injuries.
- - Researchers analyzed data from the TRACK-SCI registry, which included 72 pairs of motor examinations from 63 patients, and found strong correlations between the two methods, indicating that neurosurgery motor examinations can effectively substitute for ISNCSCI exams.
- - The results showed a very high agreement between the scores from both types of examinations with low bias, suggesting that clinical neurosurgery evaluations are reliable for assessing neurological function after spinal cord injuries.