Publications by authors named "J L Gosnell"

Article Synopsis
  • Gelatinous bone marrow transformation (GBMT) is a rare medical condition involving the atrophy of fat cells and the buildup of a gelatinous substance in the bone marrow, leading to decreased blood cell production (hypoplastic hematopoiesis).
  • A study reviewed bone marrow specimens from patients with a BMI of <18.5, revealing that 30% of those evaluated had GBMT associated with ring sideroblasts, a specific type of abnormal red blood cell.
  • Notably, one patient’s ring sideroblasts were linked to copper deficiency, highlighting that GBMT may be misdiagnosed as myelodysplastic syndrome without further investigation.
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Objective: To present the comprehensive methodology for generating personalized three-dimensional (3D) printed uterine models from 3D ultrasound (US) volumes in individuals diagnosed with Müllerian anomalies and discuss potential applications in the field of reproductive endocrinology and infertility.

Design: Pilot study.

Setting: Single large university-affiliated teaching hospital.

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Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are a growing health burden across a significant portion of the global patient population. However, these conditions seem to have disparate rates and outcomes between different ethnic populations. The combination of MASLD/MASH and type 2 diabetes increases the risk of hepatocellular carcinoma (HCC), and Hispanic patients experience the greatest burden, particularly those in South Texas.

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Introduction: Serous fluids offer crucial diagnostic insights, but inconsistent analysis hampers reporting quality, especially in indeterminate (ID) categories like atypia of undetermined significance (AUS) and suspicious for malignancy (SFM). The 2020 International System for reporting Serous Fluid Cytopathology (TIS) aims to standardize communication and reduce reporting disparities. This study evaluates TIS's role in AUS and SFM categories within our institution.

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