Ammonia and beyond - biomarkers of hepatic encephalopathy.

Ammonia is a product of amino acid metabolism that accumulates in the blood of patients with liver cirrhosis, leading to neurotoxic effects and hepatic encephalopathy (HE). HE manifestations can range from mild, subclinical disturbances in cognition, or minimal HE (mHE) to gross disorientation and coma, a condition referred to as overt HE. Many blood-based biomarkers reflecting these neurotoxic effects of ammonia and liver disease can be measured in the blood allowing the development of new biomarkers to diagnose cirrhosis patients at risk of developing HE.

Enhanced remediation of organotin compounds and metal(loid)s in polluted sediments: Chemical stabilization with mining-wastes and nZVI versus physical soil washing.

Here we describe two innovative approaches for remediating sediments contaminated with organotin compounds (OTCs, mainly TBT) and metal(loid)s. The first involves chemical stabilization through amendments with nanoscale zero-valent iron (nZVI), dunite mining waste, and coal tailings, materials that have not been previously studied for OTC remediation. The second focuses on physical soil washing, using grain-size separation and magnetic separation to isolate the most polluted fractions, thereby reducing the volume of contaminated material destined for landfills.

Correction: Inequality of the crowding-out effect of tobacco expenditure in Colombia.

[This corrects the article DOI: 10.1371/journal.pone.

Coordinative Self-assembly of π-Electron Magnetic Porphyrins.

π-Electron magnetic compounds on surfaces have emerged as a powerful platform to interrogate spin interactions at the atomic scale, with great potential in spintronics and quantum technologies. A key challenge is organizing these compounds over large length scales, while elucidating their resulting magnetic properties. Herein, we offer a relevant contribution toward this objective, which consists of using on-surface synthesis coupled with coordination chemistry to promote the self-assembly of π-electron magnetic porphyrin species.