Publications by authors named "J L Fullerton"
Deficits in neurogenesis markers in the subependymal zone (SEZ) are associated with elevated inflammation in schizophrenia and bipolar disorder. However, the extent to which complement factors are also changed in the SEZ of these major psychiatric disorders and their impact on neurogenesis remains poorly understood. We extracted RNA from the SEZ of 93 brains, including controls (n = 32), schizophrenia (n = 32), and bipolar disorder (n = 29) cases.
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- * A study compared brain tissue from 81 pediatric patients and 62 adult patients who suffered moderate to severe TBI to assess brain swelling and blood-brain barrier (BBB) integrity.
- * Results showed that pediatric patients exhibited more widespread brain swelling, primarily affecting microvascular structures, while adults displayed significant BBB disruption mainly at a larger scale, indicating different pathological mechanisms between the two age groups.
Article Synopsis
- Structural neuroimaging studies reveal both common and disorder-specific gray matter deficits across various psychiatric conditions.
- Large-scale data pooling helps identify potential neuroanatomical factors linked to mental illness vulnerability, although data-sharing faces significant challenges.
- Using a federated analysis across eight research sites, the study found overlapping gray matter patterns in schizophrenia, major depressive disorder, and autism spectrum disorder, suggesting shared cortical and subcortical vulnerabilities.
Introduction: Youth with a family history of bipolar disorder (At-Risk) have a higher risk of developing psychiatric disorders and experiencing environmental stressors than youth without such family history (Control). We studied the differential associations of familial and environmental factors on developing psychiatric diagnoses and symptoms, in At-Risk and Control youth.
Methods: At-Risk and Control youth (N = 466, ages 9-22) were systematically assessed for severity of symptoms, psychiatric diagnoses, and self-reported measures of stress and social support.
Article Synopsis
- The research investigates how manipulating spin-phonon coupling in two-dimensional van der Waals ferromagnetic semiconductors can enhance magnetism, opening new possibilities for spintronic devices.
- The study uses tetrabutyl ammonium (TBA) as an intercalant to show its effects on the magnetic and electronic properties of CrGeTe, revealing increased ferromagnetic Curie temperature through temperature evolution of Raman modes and magnetization measurements.
- The findings point to significant electron transfer from TBA to Cr, emphasizing the importance of spin-phonon interaction and magnetic ordering in understanding and controlling magnetism in layered structures.