Publications by authors named "J L Fierro"

Human lactoferrin (hLf) is an innate host defense protein that inhibits microbial H-ATPases. This protein includes an ancestral structural motif (i.e.

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Article Synopsis
  • The study focused on ventilator-dependent infants and children with bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) to assess their health outcomes.
  • Approximately 60% of the 154 subjects had pulmonary hypertension, with many requiring specific medications; those with PH tended to transition to home ventilation and discharge at older ages.
  • Despite the challenges, most subjects improved over time, successfully weaning off oxygen and ventilators by age 5, with a low mortality rate after discharge.
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Background: To enhance patient-tailored preconception risk assessment for women with systemic lupus erythematosus (SLE), knowledge on risk factors associated with adverse pregnancy outcomes is required. Therefore, we did a systematic review and meta-analysis to identify and provide unambiguous effect sizes of preconception predictors of pregnancy outcomes in women with SLE.

Methods: In this systematic review and meta-analysis, we searched PubMed and Embase for studies reporting preconception predictors of pregnancy outcomes in women with SLE, from database inception to Aug 22, 2023.

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  • The study aimed to assess the link between indoor air pollution and respiratory issues in children with bronchopulmonary dysplasia (BPD) under 3 years old.
  • It involved 1,011 participants, with over 40% exposed to indoor pollutants like tobacco smoke and gas stoves, revealing higher odds of emergency visits and antibiotic use associated with secondhand smoke exposure.
  • While acute respiratory problems were related to indoor air pollution, chronic respiratory symptoms and rescue medication use showed no significant association.
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