Human naïve B cells recognize prepandemic influenza virus hemagglutinins.

Understanding the naïve B cell repertoire and its specificity for potential zoonotic threats, such as the highly pathogenic avian influenza (HPAI) H5Nx viruses, may allow prediction of infection- or vaccine-specific responses. However, this naïve repertoire and the possibility to respond to emerging, prepandemic viruses are largely undetermined. Here, we profiled naïve B cell reactivity against a prototypical HPAI H5 hemagglutinin (HA), the major target of antibody responses.

Electroencephalographic Depth-of-Anesthesia Monitoring.

EEG-based DoA monitoring is a powerful tool for ensuring the optimal balance between maintaining unconsciousness and preventing excessive sedation during procedures. Understanding the role, indications, equipment, and troubleshooting of EEG-based DoA monitoring is necessary for the effective use of this tool in clinical decision-making.

Paternal activation parenting and growth in children's inhibitory control across early childhood.

Activation parenting (AP) is a parenting construct derived from research and theory on paternal caregiving that includes behaviors that challenge children to approach novel situations, explore their environments, and take physical and socioemotional risks through a balance of encouragement and limit-setting. Although components of AP have been linked to different domains of children's self-regulation skills, comprehensive measures of AP and longitudinal research on families from low socioeconomic backgrounds are lacking. These limitations greatly constrain our understanding of the potential benefits of paternal AP for children's self-regulation development, including the maturation of inhibitory control (IC) in early childhood.

The role of dynamic shape cues in the recognition of emotion from naturalistic body motion.

Human observers can often judge emotional or affective states from bodily motion, even in the absence of facial information, but the mechanisms underlying this inference are not completely understood. Important clues come from the literature on "biological motion" using point-light displays (PLDs), which convey human action, and possibly emotion, apparently on the basis of body movements alone. However, most studies have used simplified and often exaggerated displays chosen to convey emotions as clearly as possible.