Analyzing the basal ganglia following an early brain lesion is crucial due to their noteworthy role in sensory-motor functions. However, the segmentation of these subcortical structures on MRI is challenging in children and is further complicated by the presence of a lesion. Although current deep neural networks (DNN) perform well in segmenting subcortical brain structures in healthy brains, they lack robustness when faced with lesion variability, leading to structural inconsistencies.
View Article and Find Full Text PDFIntroduction: Neonatal arterial ischemic stroke (NAIS) is a common model to study the impact of a unilateral early brain insult on developmental brain plasticity and the appearance of long-term outcomes. Motor difficulties that may arise are typically related to poor function of the affected (contra-lesioned) hand, but surprisingly also of the ipsilesional hand. Although many longitudinal studies after NAIS have shown that predicting the occurrence of gross motor difficulties is easier, accurately predicting hand motor function (for both hands) from morphometric MRI remains complicated.
View Article and Find Full Text PDFComput Methods Programs Biomed
February 2022
Background And Objectives: In order to study neural plasticity in immature brain following early brain lesion, large animal model are needed. Because of its morphological similarities with the human developmental brain, piglet is a suitable but little used one. Its study from Magnetic Resonance Imaging (MRI) requires the development of automatic algorithms for the segmentation of the different structures and tissues.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
May 2019
This paper presents a method for recovering and identifying image regions from an initial oversegmentation using qualitative knowledge of its content. Compared to recent works favoring spatial information and quantitative techniques, our approach focuses on simple a priori qualitative inclusion and photometric relationships such as "region A is included in region B", "the intensity of region A is lower than the one of region B" or "regions A and B depict similar intensities" (photometric uncertainty). The proposed method is based on a two steps' inexact graph matching approach.
View Article and Find Full Text PDFThe proposed approach exploits a priori known qualitative inclusion and photometric relationships between image regions, represented by oriented graphs. Our work assumes a sequential image segmentation procedure where regions are progressively segmented and recognized by associating them with corresponding nodes in graphs related to the prior knowledge. The main contribution concerns the parameterization of the k-means clustering algorithm, to be used during the segmentation procedure, and the graph-matching-based identification of resulting clusters, corresponding to regions declared in graphs.
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