Nutritional Benefits and Consumer Acceptance of Maize Chips Combined with Alternative Flours.

This study evaluated the nutritional composition, techno-functional properties, and sensory acceptance of tortilla chips made from alternative flours derived from local ingredients, including maize, beet, flaxseed, bean, and chia. Three blends were assessed: maize with beans, maize with beet, and maize with chia-flaxseed. Significant differences ( < 0.

Specificity of a polygenic score for aggressive prostate cancer.

To address the concern that polygenic hazard scores for prostate cancer (PCa) might not distinguish between indolent and aggressive disease, we performed analyses using a 601-variant polygenic score (PHS601). We hypothesized that among men who eventually developed PCa, those with higher PHS were more likely to develop aggressive disease. We analyzed genetic and phenotypic data from a diverse, national cohort of men diagnosed with PCa (Million Veteran Program, n = 69,901, 6413 metastatic).

Transportation Barriers and Diabetes Outcomes: A Longitudinal Analysis.

Objective: To estimate associations between transportation barriers and diabetes outcomes.

Methods: Longitudinal cohort study; 86 977 adults with type 2 diabetes mellitus in community-based health centers were assessed for transportation barriers, with up to 36 months of follow-up after initial assessment. We compared scenarios in which individuals did not experience transportation barriers to scenarios in which they did, to estimate differences in mean hemoglobin a1c (HbA1c), systolic and diastolic blood pressure (SBP and DBP), and LDL cholesterol.

Transcriptomic neuron types vary topographically in function and morphology.

Neuronal phenotypic traits such as morphology, connectivity and function are dictated, to a large extent, by a specific combination of differentially expressed genes. Clusters of neurons in transcriptomic space correspond to distinct cell types and in some cases-for example, Caenorhabditis elegans neurons and retinal ganglion cells-have been shown to share morphology and function. The zebrafish optic tectum is composed of a spatial array of neurons that transforms visual inputs into motor outputs.

The Combined and Comparative Impacts of Financial Incentives Versus Practice Facilitation Implementation Support for Social Risk Screening in Community Health Centers.

Objective: To examine the impact of two interventions aimed at increasing the adoption of social risk screening in community health centers (CHCs).

Study Setting And Design: Intervention CHCs were in one of three groups, which received either: (1) tailored practice facilitation-focused social risk screening implementation supports; (2) financial incentives for screening; and (3) both practice facilitation and financial incentives in staggered order. A group of control clinics was identified through propensity score matching and a difference-in-difference analysis compared effects across groups.