Publications by authors named "J L Coombes"

It is now well established that vascular aging is a significant predictor of cognitive decline in older age. But what remains less clear is the role that vascular health plays in social cognitive aging. Therefore, we aimed to provide the first test of the relationship between arterial stiffness and theory of mind (ToM) in late adulthood.

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Objective: To measure current levels and experiences of food and water security in Walgett to guide a community-led program and to provide a baseline measure.

Design: A community-led cross-sectional survey conducted in April 2022 by trained local researchers.

Setting: Walgett, a regional town in NSW, Australia.

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Background: Cryptosporidiosis is a diarrheal disease that commonly affects calves under 6 weeks old. The causative agent, Cryptosporidium parvum, has been associated with the abundance of specific taxa in the faecal microbiome during active infection. However, the long-term impact of these microbiome shifts, and potential effects on calf growth and health have not yet been explored in depth.

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Article Synopsis
  • The study aimed to find the cardiorespiratory fitness (CRF) levels necessary for older adults (70-77 years) to reduce their risk of death, hypothesizing that higher peak oxygen uptake (VO) would be protective.
  • The research included a cohort of 1,565 older adults in Norway, who underwent VO testing and were monitored for all-cause mortality over five years.
  • Results indicated that lower VO levels (less than 26.5 mL/kg/min for men and 22.2 mL/kg/min for women) significantly increased the risk of death, emphasizing the need for maintaining or improving CRF in later life.
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Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.

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