Can false memories that were suppressed at one time spontaneously recover at a later time? Fuzzy trace theory and activation-monitoring theory predict that false memories in the Deese, Roediger, and McDermott (DRM) procedure become substantially reduced as list learning progresses because participants employ a memory-editing process. It follows that if the editing process is rendered less effective, false memories should spontaneously recover. We found that after DRM lists were well learned and false recognition to critical words was substantially reduced by multiple study-test trials, those false memories spontaneously recovered when participants were either rushed or delayed on a retest.
View Article and Find Full Text PDFCompared to either drug alone, therapy with the combination of ribavirin and interferon-alpha leads to improved rates of response in patients with chronic hepatitis C. Side effects often mandate downward dose adjustment or cessation of therapy, and the optimal dose of ribavirin has not been established. The aim of this study was to learn whether 600 mg ribavirin per day would prove as efficacious as 1,000-1,200 mg/day when combined with interferon (3 million units thrice weekly) for therapy of patients previously treated with standard interferon who had failed to respond or who had relapsed.
View Article and Find Full Text PDFSecretory villous adenomas of the colon have been known to cause a depleting syndrome characterized by dehydration, prerenal azotemia, hyponatremia, hypokalemia, metabolic acidosis, obtundation, and, in severe cases, death. We describe 1 case of classic depleting syndrome and review the literature on possible mechanisms. Both cyclic adenosine monophosphate and prostaglandin E2 have been implicated as possible secretagogue compounds in the pathogenesis of this syndrome unique to the secretory variant form of villous adenomas.
View Article and Find Full Text PDFThe sarcoplasmic reticulum (S.R.) of rabbit skeletal muscle has been found to contain a single, high affinity binding site for the Ca antagonist drug [3H]-nitrendipine.
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