Publications by authors named "J L Castano-Fernandez"

Article Synopsis
  • - A study evaluated the effectiveness and safety of dupilumab for treating bullous pemphigoid in elderly patients, with a focus on those who typically have other health issues that make standard treatments unsuitable.
  • - The results showed that 53.4% of patients achieved complete remission within 4 weeks and 95.7% by week 52, with a significant reduction in itchiness and a dramatic decrease in the need for corticosteroids.
  • - The treatment was found to be safe, with most adverse events being mild, and factors like shorter disease duration and exclusive skin involvement were linked to better treatment responses.
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Article Synopsis
  • Bullous pemphigoid (BP) is a common autoimmune blistering condition usually affecting older adults with various health issues, traditionally treated with corticosteroids, which have numerous side-effects.* -
  • A study assessed the use of omalizumab, an IgE-targeting monoclonal antibody, for treating BP in patients who had previously used other therapies, finding that 83% of patients responded to the treatment.* -
  • The results showed that omalizumab was well-tolerated with no reported side-effects, highlighting its potential as a safer and effective alternative for BP treatment compared to conventional therapies.*
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The present global outbreak of monkeypox has reached more than 79,000 cases by November 2022. While clinical features have been extensively studied, ultrasound findings in monkeypox skin lesions have not been described to date. In our work, we performed a complete sonographic study with Doppler and elastography of 3 patients with polymerase chain reaction-proven monkeypox.

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