A Novel Biosynthetic Gene Cluster Across the Species Complex Is Important for Pathogenicity in Onion.

Onion center rot is caused by at least four species of genus (, , , and subsp). Critical onion pathogenicity determinants for were recently described, but whether those determinants are common among other onion-pathogenic species remains unknown. In this work, we report onion pathogenicity determinants in subsp and We identified two distinct secondary metabolite biosynthetic gene clusters present separately in different strains of onion-pathogenic subsp.

Identifying prognostic structural features in tissue sections of colon cancer patients using point pattern analysis.

Diagnosis and prognosis of cancer are informed by the architecture inherent in cancer patient tissue sections. This architecture is typically identified by pathologists, yet advances in computational image analysis facilitate quantitative assessment of this structure. In this article, we develop a spatial point process approach to describe patterns in cell distribution within tissue samples taken from colorectal cancer (CRC) patients.

Evidences of strong sources of DFe and DMn in Ryder Bay, Western Antarctic Peninsula.

The spatial distribution, biogeochemical cycling and external sources of dissolved iron and dissolved manganese (DFe and DMn) were investigated in Ryder Bay, a small coastal embayment of the West Antarctic Peninsula, during Austral summer (2013 and 2014). Dissolved concentrations were measured throughout the water column at 11 stations within Ryder Bay. The concentration ranges of DFe and DMn were large, between 0.

Towards the elimination of paediatric tuberculosis in high-income, immigrant-receiving countries: a 25-year conventional and molecular epidemiological case study.

The epidemiology of tuberculosis (TB) in high-income countries is increasingly dictated by immigration. The influence of this trend on paediatric TB and TB elimination are not well defined. We undertook a 25-year conventional and molecular epidemiologic study of paediatric TB in Alberta, one of four major immigrant-receiving provinces in Canada.