Publications by authors named "J L Bourrain"

Article Synopsis
  • This review focuses on identifying individuals at risk for Hymenoptera venom-induced anaphylaxis (HVA), aiming to improve preventative strategies through different perspectives like epidemiology and therapeutics.
  • HVA is a major cause of anaphylaxis with significant emergency admissions, often underestimated in terms of mortality due to lack of recognition and witnesses, highlighting the importance of targeting risk factors for better outcomes.
  • The study emphasizes the need for personalized management approaches for HVA, noting that factors such as elevated basal serum tryptase and specific cardiovascular conditions can worsen reactions, while also acknowledging the challenges in obtaining consistent epidemiological data.
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Background: Local anesthetics (LA) are widely used in medicine and are generally well tolerated. Although most adverse reactions are nonallergic, LA are a frequent reason for allergy consultation.

Objective: We want to expand the differential diagnosis of adverse reactions to LA by presenting rare diagnoses.

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Article Synopsis
  • An aqueous antiseptic containing chlorhexidine digluconate, benzalkonium chloride, and benzyl alcohol (CBB) is commonly used in France, but its potential to cause allergic contact dermatitis (ACD) has been inadequately studied previously.
  • A retrospective study analyzed 102 patients with confirmed ACD to CBB, revealing extensive skin lesions in 63% of cases and a significant delay in diagnosis for 55% of patients.
  • Positive patch tests for CBB were found in 93.8% of patients, with benzyl alcohol being the main allergen in adults and chlorhexidine digluconate in children, indicating distinct sensitization profiles between age groups.*
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