Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy.

Surgical success for patients with focal drug resistant epilepsy (DRE) relies on accurate localization of the epileptogenic zone (EZ). Currently, no exam delineates this zone unambiguously. Instead, the EZ is approximated by the area where seizures begin, which is identified manually through a tedious process that is prone to errors and biases.

Workplace Injury and Mental Health Outcomes.

Importance: Workplace injury is a widespread problem that impacts mental health and quality of life and places a substantial burden on employers and the health care system.

Objective: To determine whether mental disorder rates differ following workplace injury compared with injuries outside the workplace.

Design, Setting, And Participants: This retrospective cohort study assessed individuals hospitalized for an injury requiring surgery between January 1, 2002, and December 31, 2018, with a 2-year follow-up period using population-based administrative data in Manitoba, Canada.

Evaluating the effectiveness of medical therapy in infantile epileptic spasms syndrome due to surgically-remediable lesions.

Objective: This single-center retrospective study examined the response to initial standard therapy in children with infantile epileptic spasms syndrome (IESS) associated with surgically-remediable lesion and evaluated the risk factors for drug resistance. We assessed whether the failure of the first standard therapy for surgically-remediable IESS predicted eventual drug resistance.

Methods: New-onset IESS with surgically-remediable lesions was included.

Association Between Nonfatal Self-Injury and Survival Following a Cancer Diagnosis: A Comparative Population-Based Cohort Study.

Background: Nonfatal self-injury (NFSI) following a cancer diagnosis is a very serious mental health sequalae. Whether NFSI has an impact on patient outcomes is unknown. To help determine the impact and burden of NFSI in cancer care, this study examined the association between NFSI following a cancer diagnosis and subsequent overall survival (OS).

Mental health in public safety personnel with workplace injuries requiring surgery: a longitudinal population-wide administrative data study in Manitoba, Canada.

Objectives: Public safety personnel (PSP) are responsible for ensuring the safety and security of communities, often putting their own lives and well-being at risk by performing dangerous and demanding work. As a result, these workers are particularly vulnerable to workplace-related physical and mental traumatic injuries. Research is needed to understand the mental health of PSP following traumatic physical injury to inform effective prevention programmes and interventions.