Publications by authors named "J L Boldsen"
Article Synopsis
- The CCR5 receptor is linked to susceptibility to Staphylococcus aureus leukotoxin ED, and researchers investigated the effects of the CCR5Δ32 deletion on S. aureus infection and nasal carriage in a large Danish blood donor study.
- Analysis involved over 95,000 participants, examining various health outcomes and inflammatory markers through sophisticated statistical methods.
- Findings indicated that CCR5Δ32 does not significantly affect the risk of S. aureus-related infections or nasal carriage, although it was associated with higher levels of certain chemokines in individuals with the deletion.
Background: The emerging use of biomarkers in research and tailored care introduces a need for information about the association between biomarkers and basic demographics and lifestyle factors revealing expectable concentrations in healthy individuals while considering general demographic differences.
Methods: A selection of 47 biomarkers, including markers of inflammation and vascular stress, were measured in plasma samples from 9876 Danish Blood Donor Study participants. Using regression models, we examined the association between biomarkers and sex, age, Body Mass Index (BMI), and smoking.
is the causative agent of at least three major plague pandemics (Justinianic, Medieval and Modern). Previous studies on ancient genomes revealed that several genomic alterations had occurred approximately 5000-3000 years ago and contributed to the remarkable virulence of this pathogen. How a subset of strains evolved to cause the Modern pandemic is less well-understood.
View Article and Find Full Text PDFBackground: The identification of blood donors at risk of developing low hemoglobin (Hb) and subsequent intervention is expected to reduce donation-induced iron deficiency and low Hb among blood donors. This study explores the effects of ferritin-guided iron supplementation for female first-time donors implemented in four of five administrative regions in Denmark.
Study Design And Methods: We included 45,919 female first-time donors in this study.