Publications by authors named "J L Birley"

Article Synopsis
  • Acute appendicitis remains difficult to diagnose in children, leading to high misdiagnosis and complication rates, which highlights the need for new diagnostic tools.
  • Recent findings suggest a link between low serum sodium levels (hyponatremia) and complicated appendicitis, potentially influenced by inflammatory responses.
  • A meta-analysis of seven studies revealed significantly lower serum sodium levels in children with complicated appendicitis compared to those with uncomplicated cases, indicating hyponatremia could serve as a potential diagnostic marker.
View Article and Find Full Text PDF

Background: The treatment of congenital melanocytic naevi (CMNs) has become controversial as better data on complications have been published.

Objectives: To determine the longer-term risks and benefits of surgery in treatment of CMNs.

Methods: In this 19-year prospective study, 301 families completed yearly questionnaires about treatments and CMN changes.

View Article and Find Full Text PDF

Background: The aetiology of congenital melanocytic naevi (CMNs) is unknown.

Objectives: To identify potential aetiological factors in families of children with CMNs, and to relate these to long-term outcome measures.

Methods: Three hundred and forty-nine CMN families completed questionnaires about pregnancy and parental factors, and yearly questionnaires on the health of their child and details of the CMN.

View Article and Find Full Text PDF