Publications by authors named "J L Bidwell"
Objectives: Advance care planning (ACP) supports communication and medical decision-making and is best conceptualized as part of the care planning continuum. Black older adults have lower ACP engagement and poorer quality of care in serious illness. Surrogates are essential to effective ACP but are rarely integrated in care planning.
View Article and Find Full Text PDFObjective: To execute a large-scale, decentralized, clinical-grade whole exome sequencing study, coined Tapestry, for clinical practice, research discovery, and genomic education.
Patients And Methods: Between July 1, 2020, and May 31, 2024, we invited 1,287,608 adult Mayo Clinic patients to participate in Tapestry. Of those contacted, 114,673 patients were consented and 98,222 (65.
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) affects all cardiac chambers to cause left ventricular (LV) deformation as well as left atrial (LA) remodeling and functional impairment. We investigated the associations of the LA volume index (LAVI):LV ejection fraction (LVEF) ratio with the increased risk of death, heart transplant, or LV assist device implantation (LVAD) in patients with ATTR-CM.
Methods: This was a retrospective cohort study involving 69 heart failure (HF) patients with ATTR-CM at an academic medical center between 1 November 2008 and 31 March 2024.
Real-time augmentation of diagnostic nasal endoscopy video using AI-enabled edge computing.
Int Forum Allergy Rhinol
September 2024
AI-enabled augmentation of nasal endoscopy video images is feasible in the clinical setting. Edge computing hardware can interface with existing nasal endoscopy equipment. Real-time AI performance can achieve an acceptable balance of accuracy and efficiency.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to determine if exome sequencing could help efficiently identify individuals with hereditary breast and ovarian cancer (HBOC) and Lynch syndrome (LS), which are genetic conditions linked to increased cancer risk.
- - Over 44,000 participants were recruited across diverse regions in the U.S., resulting in the identification of 550 carriers of HBOC and LS, with 52.1% being newly diagnosed and 39.2% not meeting current genetic evaluation criteria.
- - The findings suggest a need for broader use of germline genetic screening to improve the screening and detection of those predisposed to these cancer syndromes, particularly among underrepresented populations.