Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy.

Cartilage engineering is a new strategy for the treatment of cartilage damage due to osteoarthritis or trauma in humans. Racehorses are exposed to the same type of cartilage damage and the anatomical, cellular, and biochemical properties of their cartilage are comparable to those of human cartilage, making the horse an excellent model for the development of cartilage engineering. Human mesenchymal stem cells (MSCs) differentiated into chondrocytes with chondrogenic factors in a biomaterial appears to be a promising therapeutic approach for direct implantation and cartilage repair.

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The project entitled “Study of montane ecosystems in the Malagasy region” (RCP 225/CNRS, directed by Renaud Paulian) aimed to elucidate the general features of these ecosystems and the origin of their constituent elements, and to test the validity of the High Mountain Domain proposed by Humbert in 1951. From 1970 to 1973, three expeditions (to the Andringitra, Anosy, Ankaratra, Itremo, Ibity and Marojejy massifs) provided informations to characterize the ecology of these particular environments and to analyse systematically certain groups well-known for their biogeographic interest. The altitudinal succession of plant formations, defined by physiognomic and structural criteria, were detailed for each massif.

Acquired subglottic stenosis--depth and not extent of the insult is key.

In contrast to skin, mucosal wound healing has not been extensively studied. Subglottic stenosis (SGS) is an excellent model for such investigation. The main objective of this pilot study was to develop a chronic model of SGS in a small animal (i.

Fetal airway wound repair: a new frontier.

Purpose: Fetal dermal repair is regenerative and scarless until middle to late gestation, when there is a transition to fibrotic repair. Fetal skeletal muscle and tendon undergo repair with fibrosis similar to the process in adults. This study addresses whether fetal mucosal healing is regenerative and scarless.

Anomalies of centriolar derivatives manifest in spermatic flagella and respiratory cilia of the stallion.

Anomalies of centriolar derivatives were identified in ejaculates and testicular and tracheal biopsies of a sterile stallion, using light, scanning, and transmission electron microscopy. LM revealed that over half the sperm population had only a vestigial or no tail, while the rest had tails of variable length and shape. The vestigial tail was represented by its anlage, which was implanted on the nucleus and differentiated up to capitulum and collum stage.