Publications by authors named "J L Berka"
Article Synopsis
- This research investigates whether the emergence of specific T and B cells in response to COVID-19 disrupts the overall diversity of the immune system's cell receptor repertoire.
- A genomic analysis of 95 individuals revealed that while there were expected increases in certain immune response sequences during SARS-CoV-2 infection, no significant issues were found in younger individuals.
- However, older patients (over 50) showed a concerning reduction in T cell diversity, which may increase their risk for severe COVID-19 and complicate responses to emerging variants.
Background: Disease progression of subjects with coronavirus disease 2019 (COVID-19) varies dramatically. Understanding the various types of immune response to SARS-CoV-2 is critical for better clinical management of coronavirus outbreaks and to potentially improve future therapies. Disease dynamics can be characterized by deciphering the adaptive immune response.
View Article and Find Full Text PDFHypodescent emerged in U.S. history to reinforce racial hierarchy.
View Article and Find Full Text PDFWe have developed a new separation device to concentrate and collect ions from several milliliter sample volumes to microliter fractions. Unlike most conventional platforms, this device has circular architecture. The electrophoretic migration operates from the outer perimeter toward the center.
View Article and Find Full Text PDFIn most insects, hemolymph coagulation, which is analogous to mammalian blood clotting, involves close collaboration between humoral and cellular components. To gain insights into the secretion of cellular clotting factors, we created tagged versions of three different clotting factors. Our focus was on factors which are released in a non-classical manner and to characterize them in comparison to a protein that is classically released, namely Glutactin (Glt).
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