Publications by authors named "J L Belinson"
Background: Easy-to-use, rapid, scalable, high-throughput, and cost-effective HPV tests are urgently needed for low-resource settings. Atila Biosystems' high-throughput, cost-effective, and clinically validated ScreenFire HPV Risk Stratification (RS) assay identifies 13 high risk HPV (hrHPV) in 4 groups based on their oncogenic risk (i.e.
View Article and Find Full Text PDFBackground: Despite the promise of mail-based human papillomavirus (HPV) self-collection programs for increasing cervical cancer screening, few have been evaluated in the United States. We report the results of a mail-based HPV self-collection program for underscreened women living in Appalachia.
Methods: We conducted a group randomized trial from 2021 to 2022 in the Appalachian regions of Kentucky, Ohio, Virginia, and West Virgnia.
Article Synopsis
- The study aims to validate the 2019 US risk-based guidelines for cervical cancer screening specifically for Chinese women using data from over 10,000 cases.
- Analysis revealed that the guidelines effectively recommended appropriate actions, with high sensitivity (87.1%) and specificity (82.5%) for detecting advanced cervical lesions (CIN2+ and CIN3+) while also effectively identifying lower-risk cases.
- Overall, the findings suggest that the US risk-based guidelines are applicable and reliable for cervical cancer screening in China, indicating their potential to enhance public health efforts in this area.
Objectives: The human papillomavirus (HPV) screening assays from Atila Biosystems, including the new AmpFire (14 type) and ScreenFire RS (13 type), were subjected to a series of validation tests.
Methods: We used a set of samples from the Chinese Multi-Site Screening Trial (previously tested with cobas 4800 and the next-generation SeqHPV) to satisfy Meijer's criteria for clinical end-point validation. We selected 556 self-collected specimens composed of 273 high-risk HPV (hrHPV) positives and 283 hrHPV negatives on the cobas 4800 and SeqHPV.
Objective: To evaluate the feasibility of an internet-facilitated community model for cervical cancer screening using self-collected HPV testing as primary screening.
Method: A population-based cervical cancer screening program was conducted in the suburb of Shenzhen, China, from September 2014 to July 2017. Women with 25-60 years of age and no pregnancy were eligible for participation.