Validation of an algorithm for automatic calculation of inter-lesion distance in radiofrequency catheter ablation of atrial fibrillation.

Atrial Fibrillation (AF) is a heart rhythm disorder characterized by rapid and irregular atrial contractions, which can increase the risk of stroke and decrease patients' quality of life. One of the main techniques to treat AF is RF catheter ablation, which involves electrically isolating the pulmonary veins from the rest of the atrium, based on point lesions surrounding the veins. There is still discussion in the community as to what is the optimal interlesion distance to improve the long-term results of AF ablation.

Evaluation of Diffuse Reflectance Spectroscopy Vegetal Phantoms for Human Pigmented Skin Lesions.

Pigmented skin lesions have increased considerably worldwide in the last years, with melanoma being responsible for 75% of deaths and low survival rates. The development and refining of more efficient non-invasive optical techniques such as diffuse reflectance spectroscopy (DRS) is crucial for the diagnosis of melanoma skin cancer. The development of novel diagnostic approaches requires a sufficient number of test samples.

Digital Histopathological Discrimination of Label-Free Tumoral Tissues by Artificial Intelligence Phase-Imaging Microscopy.

Histopathology is the gold standard for disease diagnosis. The use of digital histology on fresh samples can reduce processing time and potential image artifacts, as label-free samples do not need to be fixed nor stained. This fact allows for a faster diagnosis, increasing the speed of the process and the impact on patient prognosis.

Cytotoxicity analysis of oxazine 4-perchlorate fluorescence nerve potential clinical biomarker for guided surgery.

Biological tissue discrimination is relevant in guided surgery. Nerve identification is critical to avoid potentially severe collateral damage. Fluorescence imaging by oxazine 4-perchlorate (O4P) has been recently proposed.