Publications by authors named "J L Adda"

Objective: We aimed to describe characteristics of patients with ATTR variant polyneuropathy (ATTRv-PN) and ATTRv-mixed and assess the real-world use and safety profile of tafamidis meglumine 20mg.

Methods: Thirty-eight French hospitals were invited. Patient files were reviewed to identify clinical manifestations, diagnostic methods, and treatment compliance.

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Owing to advances in medical and surgical fields, patients with single ventricle (SV) have a greatly improved life expectancy. However, progressive functional deterioration is observed over time, with a decrease in cardiopulmonary fitness. This study aimed to identify, in patients with SV, the association between cardiac magnetic resonance imaging (CMR) parameters and change in cardiopulmonary fitness assessed by cardiopulmonary exercise test (CPET), and if certain thresholds could anticipate a decline in aerobic fitness.

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Half of the patients with heart failure (HF) have preserved ejection fraction (HFpEF). To date, there are no specific markers to distinguish this subgroup. The main objective of this work was to stratify HF patients using current biochemical markers coupled with clinical data.

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Background: Pheochromocytoma is an endocrine tumour secreting catecholamines, most often revealed by clinical symptoms (headache, palpitations, diaphoresis, or resistant hypertension). Some cases of ventricular arrhythmias were described in the literature, without any formal link between arrhythmia and pheochromocytoma.

Case Summary: We report a case of pheochromocytoma discovered after cardiac arrest due to ventricular fibrillation in a 46-year-old patient.

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Background: Planimetry of aortic stenosis can be performed when Doppler measurements are unavailable. We sought to evaluate if, as advised in guidelines, the geometric orifice area (GOA) threshold value of 1 cm² was concordant with the threshold of 1 cm² of the effective orifice area (EOA), and the factors influencing the contraction coefficient (EOA/GOA ratio).

Methods: In an in vitro mock circulatory system, we tested 6 degrees of AS severity (3 severe and 3 non-severe), and 3 levels of flow (<150 ml/s, 150-200 ml/s, >250 ml/s).

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