Publications by authors named "J Kvetina"
Background: There is no single gold standard for investigation of gastrointestinal motility function. Wireless motility monitoring involves a novel concept which provides a complex information on gastrointestinal function (gastrointestinal transit time, intra-luminal pH, pressure and temperature). Gastrointestinal motility functions of experimental pigs are very similar to those of humans.
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- Rivastigmine is a cholinesterase inhibitor used for treating Alzheimer's disease and can cause gastrointestinal side effects, which this study aimed to investigate through its effects on gastric function in pigs.
- Six female pigs were divided into two groups to receive either a single dose or a repeated daily dose of rivastigmine, followed by monitoring their gastric activity using electrogastrography (EGG).
- Results indicated that both single and repeated doses of rivastigmine significantly affected gastric motility, with notable changes in EGG power and dominant frequency observed in both groups.
The Effect of Lactobacillus casei on Experimental Porcine Inflammatory Bowel Disease Induced by Dextran Sodium Sulphate.
Acta Medica (Hradec Kralove)
September 2021
Background: Gastrointestinal injury caused by dextran sodium sulphate (DSS) is a reliable porcine experimental model of inflammatory bowel disease (IBD). The purpose of this study was to evaluate the effect of probiotic Lactobacillus casei DN 114001 (LC) on DSS-induced experimental IBD.
Results: Eighteen female pigs (Sus scrofa f.
Galantamine has been used as a treatment for Alzheimer disease. It has a unique, dual mode of action (inhibitor of acetylcholinesterase and allosteric modulator of nicotinic acetylcholine receptors). Nausea (in about 20%), vomiting (10%) and diarrhoea (5-7%) are the most common side effects.
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