Publications by authors named "J Kuschyk"
Article Synopsis
- Inappropriate therapy (IAT) is a significant issue associated with implantable cardiac defibrillator (ICD) therapy, particularly highlighted in early subcutaneous ICD (S-ICD) studies which showed high rates of inappropriate shocks (IAS).
- The PRAETORIAN trial, an international study with 849 patients, found no major differences in IAT and IAS rates between S-ICD and transvenous ICD (TV-ICD) groups, as both groups had similar cumulative incidences.
- Key predictors for IAT varied between the two groups, with TV-ICD patients experiencing IAT mainly from supraventricular tachycardias, while S-ICD patients faced issues from cardiac oversensing
Article Synopsis
- The S-ICD was created to eliminate lead-related issues found in the TV-ICD, as it is an external device that sits under the skin rather than using leads inside the body.
- This analysis comes from the PRAETORIAN trial, where patients were randomly assigned to either S-ICD or TV-ICD and assessed for quality of life through various questionnaires at different stages.
- Results showed no significant differences in physical and mental well-being between the groups, but patients who experienced a shock recently reported lower social functioning and emotional health compared to those who did not.
Article Synopsis
- Cardiac implantable devices like CRT-Ds and CCMs are options for patients with heart failure and reduced left ventricular function despite medical treatment, but a direct comparison between the two has not been done before.* -
- The study analyzed data from two registries to compare 220 CRT-D patients and 105 CCM patients, finding that before treatment, CCM patients had worse heart function; however, both groups showed similar improvements after 12 months.* -
- Despite comparable functional improvements, CCM patients had significantly higher rates of heart failure hospitalizations (45.7% compared to 16.8% for CRT-D patients), indicating a potential downside to CCM therapy.*
Cardiac resynchronization therapy with implantable cardioverter defibrillators (CRT-Ds) are established therapy options for patients suffering from heart failure (HF). Several aspects of HF modification have yet to be described regarding etiology-dependent outcome differences in the long-term.The Mannheim CArdiac Resynchronization TherApy RetrospeCtive ObservAtioNAl (MARACANA) Registry retrospectively included all patients provided with CRTs in our center from 2013 to 2021.
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- The study aims to evaluate the performance and safety of subcutaneous-implantable cardioverter defibrillator (S-ICD) technology in athletes compared to nonathletes, focusing on device-related complications and shock occurrences.
- Athletes made up 10.2% of the 1493 patients studied and showed higher incidences of certain heart conditions, with a tendency to experience appropriate shocks more frequently during exercise, although this was not statistically significant after adjusting for other factors.
- Overall, S-ICDs appear to be a safe option for athletes, as there was no significant difference in overall complications or inappropriate shocks between the two groups, though athletes had a higher risk of myopotential oversensing and lead infections shortly after implant.