Purpose: The immunodominant TSA 56 gene of Orientia tsutsugamushi, (scrub typhus agent) has four variable regions (VD-I to VD-IV) making it useful for genotyping. This study was undertaken to determine Orientia tsutsugamushi genotypes circulating in and around Vellore using complete and partial TSA 56 gene.
Methods: Of the 162 patients positive by 47 kDa qPCR, on 21 samples PCR to amplify the complete TSA 56 gene (≈1605 bp: Long protocol) and the partial gene sequence using the Horinouchi (≈650bp) and the Furuya (≈480 bp) protocol was performed.
Faja corset, a tight garment worn to obtain an hourglass body, may have contributed to the formation of a spontaneous subcapsular hematoma in a 38-year-old nulligravid woman with no history of trauma. Subcapsular hematomas of the liver are a rare occurrence, with many documented cases arising during pregnancy as a complication of HELLP (hemolysis, elevated liver enzymes, and low platelet) syndrome. Additional causes include iatrogenic trauma, rupture of cysts, hepatic adenomas, hepatocellular carcinoma, or coagulopathies.
View Article and Find Full Text PDFMillions of Americans smoke cannabis every day. With the recent legalization of cannabis in many states, the number of Americans who smoke cannabis is expected to climb even higher. This case report presents a chronic cannabis smoker who developed severe Barrett's esophagus at a young age.
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