Publications by authors named "J Kubanek"

Emerging neurostimulation methods aim to selectively modulate deep brain structures. Guiding these therapies has presented a substantial chal- lenge, since imaging modalities such as MRI limit the spectrum of benefi- ciaries. In this study, we assess the guidance accuracy of a neuronavigation method that does not require taking MRI scans.

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Article Synopsis
  • A novel noninvasive method combines magnetic and focused ultrasonic fields to create electric fields deep in the brain for potential treatments of mental and neurological disorders.
  • This study tested this method on non-human primates' visual circuits, examining the effects of different ultrasonic pulse frequencies on neural activity.
  • Results showed that low-frequency stimulation (5 Hz) inhibited brain activity, while higher frequencies did not, indicating the importance of pulse frequency in neuromodulation without safety concerns.
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In May and June of 2021, marine microbial samples were collected for DNA sequencing in East Sound, WA, USA every 4 hours for 22 days. This high temporal resolution sampling effort captured the last 3 days of a Rhizosolenia sp. bloom, the initiation and complete bloom cycle of Chaetoceros socialis (8 days), and the following bacterial bloom (2 days).

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Article Synopsis
  • Severe depression is associated with high activity in the subcallosal cingulate (SCC), and while surgical stimulation can help, existing noninvasive methods haven't targeted deep brain areas effectively.
  • A study involving 22 participants tested a new technique using low-intensity focused ultrasonic waves to stimulate the SCC while also measuring brain activity and mood changes.
  • Results showed that this stimulation reduced SCC activity and led to significant improvements in mood and depression scores compared to a sham treatment, suggesting potential for new therapeutic approaches targeting deep brain circuits.
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In May and June of 2021, marine microbial samples were collected for DNA sequencing in East Sound, WA, USA every 4 hours for 22 days. This high temporal resolution sampling effort captured the last 3 days of a sp. bloom, the initiation and complete bloom cycle of (8 days), and the following bacterial bloom (2 days).

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