Renal transplantation for type II diabetic patients compared with type I diabetic patients and patients over 50 years old: a single-center experience.

Introduction: Transplantation of renal allografts for Type II diabetic patients has become increasingly common. Like Type I diabetics and patients over age 50, Type II diabetics are in a high-risk category for renal transplantation. Some investigators argue that the scarce resources of the valuable donor pool should not be allocated to these high-risk, older individuals with end-stage renal disease (ESRD) who often have significant comorbidity.

The effect of hypercholesterolemia on the rabbit transarterial wall oxygen gradient.

The objective of this study was to determine the effect of hypercholesterolemia on the transarterial wall oxygen gradient. Female New Zealand white rabbits (3-4 kg) were fed a 0.5% cholesterol supplemented diet or a 0.

Posttransplant nonfunction of canine islets in PVG rats deficient in complement component C6.

Background: Discordant islet xenografts are immediately nonfunctional in nonimmunosuppressed recipients other than the mouse, a process called primary nonfunction. Although at present it is unknown whether complement is involved, complement might participate in the induction of primary nonfunction through a number of mechanisms. We investigated the potential role of the membrane attack complex of complement in primary nonfunction of transplanted xenoislets.

Cigarette smoking alters the rabbit transarterial wall oxygen gradient.

The objective of this study is to determine the effect of short-term (3 weeks) and long-term (10 weeks) cigarette smoking on the transarterial wall oxygen gradient. Female New Zealand White Rabbits (3-4 kg) were exposed to the smoke of seven nonfiltered cigarettes daily and their transarterial wall oxygen gradients measured at 3 weeks or 10 weeks before and during cigarette smoke exposure. Arterial blood oxygen content, percent of carboxyhemoglobin, and arterial blood pressure were recorded during the experiments.