The results of a systematic examination of the UV/VIS spectra of 10 drug substances with chromophores and auxochromes in bicyclic and tricyclic systems (benzodiazepine, dibenzoazepine and dibenzodiazepine) are described. Influences of substituents and solvents on shifts of the E, K, B and R bands are discussed.
View Article and Find Full Text PDFThe results of a systematic examination of the spectra of 15 drug substances with chromophores and auxochromes in monocyclic (pyrazolone, pyrazolidin, pyridazine, pyrimidine and pyrazine) and bicyclic compounds (benzoxazol, imidazole, benzthiazole and indene) in the UV and visible range were evaluated. Influences of substituents and solvents on shifts of the E, K, B and R bands were discussed.
View Article and Find Full Text PDFThe spectra of 22 drug substances with chromophores and auxochromes in the aliphatic chain, in the saturated heterocyclus and in heterocyclic compounds (furan, imidazole, thiazole, thiadiazole and oxadiazole) underwent a systematic investigation and the results obtained were evaluated. Influences of substituents and solvents on shifts of the E, K, B and R bands were discussed.
View Article and Find Full Text PDFThe behaviour of 10 new substances with benzene, pyridine and chinoline chromophores was tested in the UV and visible spectral region. Influences of substituents and solvents on shifts of the bands E, K, B and R are discussed.
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