Publications by authors named "J Kou"
The neurotransmitter gamma-aminobutyric acid (GABA) has been thought to be involved in the development of some types of cancer. Yet, the de novo synthesis of GABA and how it functions in hepatocellular carcinoma (HCC) remain unclear. Here, we report that SLC6A12 acts as a transporter of GABA, and that aldehyde dehydrogenase 9 family member A1 (ALDH9A1), not glutamate decarboxylase 1 (GAD1), generates GABA in human HCC.
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- The cold climate and poor nutrient soil in high-altitude mining areas pose challenges for ecological restoration, which could be improved by adding specific microorganisms.
- This study investigates the effects of the phosphate-solubilizing bacterium MWP-1 in enhancing soil nutrients and promoting plant growth in the Muli mining area of Qinghai Province.
- Results indicate that MWP-1 significantly boosts soil nutrients and vegetation growth, positively impacting microbial community composition and diversity, and contributes to soil remediation in the mining zone.
[Genome-wide identification and expression pattern analysis of Eucommia ulmoides Trihelix gene family].
Zhongguo Zhong Yao Za Zhi
November 2024
Trihelix transcription factors play important roles in plant light responses, growth and development, and stress responses. However, Trihelix has not yet been reported in Eucommia ulmoides. In this study, bioinformatics methods were used to comprehensively identify and analyze the expression patterns of the Trihelix gene family in E.
View Article and Find Full Text PDFEnzyme-powered nanomotors have attracted significant attention in materials science and biomedicine for their biocompatibility, versatility, and the use of biofuels in biological environments. Here, we employ a hybrid mesoscale method combining molecular dynamics and multi-particle collision dynamics (MD-MPC) to study the dynamics of nanomotors powered by enzyme reactions. Two cascade enzymes are constructed to be layered on the same surface of a Janus colloid, providing a confined space that greatly enhances reaction efficiency.
View Article and Find Full Text PDFBackground: The "Social Motivation" hypothesis posits that social deficits in autism spectrum disorder (ASD) arise from altered reward perception. However, few studies have examined neural and behavioral responses to social reward-related cues in low functioning ASD children with limited cognitive or language abilities.
Objective: This study investigated if young children with ASD show atypical gaze towards happy faces and its association with altered brain reward responses.