Publications by authors named "J Korv"
Article Synopsis
- * Researchers collected blood samples from 73 patients and analyzed the expression of specific genes and miRNAs using real-time quantitative PCR, revealing significant differences in gene expression patterns between the two types of stroke.
- * Findings showed that certain inflammatory genes were more upregulated during the acute phase of cryptogenic stroke compared to LAA stroke, suggesting differing inflammatory responses associated with these two stroke types.
Article Synopsis
- The study examined the link between heavy alcohol use and young-onset cryptogenic ischemic stroke (CIS) in individuals aged 18-49.
- Patients showed significantly higher rates of heavy drinking compared to stroke-free controls, with 13.7% of CIS patients classified as heavy alcohol users versus 6.7% of controls.
- The findings suggest that heavy alcohol consumption, especially binge drinking, is an independent risk factor for CIS in young men, but not in women.
Background: Anti-inflammatory therapy with long-term colchicine prevented vascular recurrence in coronary disease. Unlike coronary disease, which is typically caused by atherosclerosis, ischaemic stroke is caused by diverse mechanisms including atherosclerosis and small vessel disease or is frequently due to an unknown cause. We aimed to investigate the hypothesis that long-term colchicine would reduce recurrent events after ischaemic stroke.
View Article and Find Full Text PDFBackground: Infections and fever after stroke are associated with poor functional outcome or death. We assessed whether prophylactic treatment with anti-emetic, antibiotic, or antipyretic medication would improve functional outcome in older patients with acute stroke.
Methods: We conducted an international, 2∗2∗2-factorial, randomised, controlled, open-label trial with blinded outcome assessment in patients aged 66 years or older with acute ischaemic stroke or intracerebral haemorrhage and a score on the National Institutes of Health Stroke Scale ≥ 6.