[Computerized infusion test. II. Clinical use].

In 39 patients with intracranial lesions the resorption resistance was measured using an own computerized infusion test. A high usefulness of this test was demonstrated in the diagnosis of hydrocephalus and for establishing indications to ventriculocardiac valve implantation. In patients after craniocerebral injuries a rise was observed of the resorption resistance immediately after trauma in cases with subarachnoid haemorrhage.

[Computerized infusion test. I. The method].

Biophysical aspects and the method of the Computerized Infusion Test (CIT) developed in the Neurosurgical Clinic of the Medical Research Center, Polish Academy of Sciences, are presented. The CIT is a development of classical methods of estimating the cerebrospinal fluid outflow resistance. It is based on a clinically tested mathematical model of the intracranial pressure-volume compensating mechanisms.

CSF absorptive capacity in patients without intracranial pathology.

The role of changes in CSF inflow in patients without intracranial pathology has been studied. The CSF outflow resistance has been calculated, by dividing the CSF pressure rise by the speed of intrathecal saline infusion. The average CSF pressure rise produced during infusion test (infusion 2 ml/min) amounted to 11.

A fast method of estimating the elastance of the intracranial system.

The authors describe a fast method for estimating the elastance of the intracranial system in man. The method consists in constructing the so-called amplitude-pressure (Amp-P) curve which describes the relationship between the amplitude of pulse-related oscillations in cerebrospinal fluid pressure and the basic level of intracranial pressure. The Amp-P curve consists of two straight lines, and the point of intersection of these lines is thought to indicate the intracranial pressure level at which there occurs a qualitative change in the functioning of compensatory mechanisms of the intracranial system.