Impact of DLL3 Expression as Prognostic Factor in Extensive Stage of Small Cell Lung Cancer Treated With First-Line Chemotherapy.

Introduction: Small cell lung cancer (SCLC) is known for its high proliferative rate and poor prognosis. Although Delta-like ligand 3 (DLL3) is specifically expressed on the surface of SCLC, the association of DLL3 with prognosis in SCLC remains uncertain. Hence, we aimed to evaluate prognostic role of DLL3 in extensive stage of SCLC treated with first-line chemotherapy.

[Carbon Stock Changes and Forecasting in Xinjiang Based on PLUS and InVEST Model Approach].

Land use change is the main cause of carbon stock changes in terrestrial ecosystems. Studying the impact mechanisms of carbon stock changes in different land use types in the arid zone and simulating future changes in land use and carbon stock under different scenarios will help to formulate a scientific land use policy for the arid zone to promote high-quality and sustainable development in the region. Based on the Xinjiang land use data from 2000 to 2020, the coupled PLUS-InVEST model analyzed the spatial and temporal characteristics of land use and carbon stock in Xinjiang from 2000 to 2020 and predicted the changes in land use and carbon stock in Xinjiang in 2030 under the scenarios of natural development （Z1）, economic development （Z2）, sustainable development （Z3）, arable land preservation development （Z4）, and ecological protection development （Z5）.

Deep learning model meets community-based surveillance of acute flaccid paralysis.

Acute flaccid paralysis (AFP) case surveillance is pivotal for the early detection of potential poliovirus, particularly in endemic countries such as Ethiopia. The community-based surveillance system implemented in Ethiopia has significantly improved AFP surveillance. However, challenges like delayed detection and disorganized communication persist.

Benefit of the Omental Flap in Breast Reconstruction for Oncoplastic Treatment: A Systematic Review and Single-Arm Meta-Analysis.

Background: Oncoplastic surgery for breast cancer patients poses the challenge of achieving optimal aesthetic outcomes without increasing the risk of complications. Omental flap has emerged as n reconstructive option in breast surgery, yet the efficacy and safety of large omental flaps remain uncertain. This study aims to conduct a systematic review and single-arm meta-analysis to comprehensively evaluate the effectiveness, safety, and cosmetic outcomes of large omental flap breast reconstruction, providing updated evidence for clinical practice.

White circularly polarized luminescence from a dual-component emitter induced by FRET between tetraphenylene and PDI derivatives.

A chiral agent, TPE-ASP, incorporating aspartic acid as the chiral source and tetraphenylene derivatives as chromophores, was designed and synthesized. The chiral agent was self-assembled into regular spherical nanoparticles with a maximum luminescence asymmetry factor of |2.41 × 10| at 460 nm which is attributed to TPE-ASP.