A novel way to integrate economic information into clinical practice guidelines.

Background: Clinical guidelines are widely used to support clinical decision making, so they could also provide economic information about medical interventions to promote cost-conscious health care. We developed a new way to integrate economic information into the Finnish Current Care Guidelines.

Methods: Our development team consisted of clinical guideline specialists and health economists.

Perspectives on low-value care and barriers to de-implementation among primary care physicians: a multinational survey.

Background: Healthcare costs are rising worldwide. At the same time, a considerable proportion of care does not benefit or may even be harmful to patients. We aimed to explore attitudes towards low-value care and identify the most important barriers to the de-implementation of low-value care use in primary care in high-income countries.

The Finnish current care guideline for open-angle glaucoma.

This article is an English translation of the 4th Finnish Current Care Guideline for diagnostics, treatment and follow-up of primary open-angle glaucoma, normal-tension glaucoma and pseudoexfoliative glaucoma. This guideline is based on systematic literature reviews and expert opinions with Finland's geographical and operational healthcare environment in mind.

Linear bis-Coordinate Silver(I) and Iodine(I) Complexes with R R R N Tertiary Amines.

Homoleptic [L-I-L] iodine(I) complexes (where L is a R R R N tertiary amine) were synthesized via the [L-Ag-L] → [L-I-L] cation exchange reaction. In solution, the amines form [R R R N-Ag-NR R R ] silver(I) complexes, which crystallize out from solution as the meso-[L-Ag-L] complexes, as characterized by X-ray crystallography. The subsequent [L-I-L] iodine(I) analogues were extremely reactive and could not be isolated in the solid state.