Cytokeratin-positive interstitial reticulum cell tumor: recognition of a potential "in situ" pattern.

Cytokeratin-positive interstitial reticulum cell (CIRC) tumor is a very rare accessory cell neoplasm of lymphoid organs derived from fibroblastic reticulum cells, which originate from mesenchymal stem cells. We describe the histologic, immunophenotypical, and molecular features of a CIRC tumor in a 67-year-old woman who underwent hysterectomy, bilateral adnexectomy, and pelvic lymphadenectomy for endometrial carcinoma. An enlarged pelvic node contained circumscribed neoplastic infiltrates in perifollicular and interfollicular areas consisting of large cells arranged in a reticular pattern with nuclear atypia, atypical mitoses, and apoptosis, but without glandular architecture or disruption of overall architecture.

[Autofluorescence and endometriosis optical trap or new hope in dianosis of endometriosis?].

Laparoscopic autofluorescence imaging of endometriosis is a new method to properly detect the disease. Autofluorescence in contrast to conventional white light laparoscopy enables us to visualize the entire extent of disease and to recognize extremely small or occult lesions. Autofluorescence imaging in fact reveals a world behind the world, a substantial new representation of endometriosis, which will have much impact on our future therapeutic strategies.

[Global ablation of endometrium as a new uterus sparing operative method in uterine dysfunctional bleeding].

A new method of endometrial ablation has been presented. This is the method of bipolar tridimensional device "NOVA SURE". This innovative method enables to destruct the basal and functional layer of the uterus and thus leads to amenorrhea and hypomenorrhea.