Publications by authors named "J Klaudiny"

is the causative agent of American foulbrood (AFB), the most serious bacterial disease affecting developing honeybee larvae and pupas. In this study, a library of 24 (thio)glycosides, glycosyl sulfones, 6--esters, and ethers derived from d-mannose, d-glucose, and d-galactose having C10 or C12 alkyl chain were evaluated for their antibacterial efficacy against two strains. The efficacy of the tested compounds determined as minimal inhibitory concentrations (MICs) varied greatly.

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Article Synopsis
  • Paenibacillus larvae causes American foulbrood (AFB), a serious disease affecting honeybee larvae, with significant infestations identified in two regions of the Czech Republic from 2016-2018.
  • The study utilized techniques like ERIC genotyping, MLST, and whole genome sequencing to analyze the genetic structure of P. larvae strains, revealing that 78.9% belonged to the ERIC II genotype and identified six sequence types.
  • Findings indicated that each heavily infested area had its own dominant strains, hinting at local infection sources while also showing some strains in distant areas, suggesting potential human-mediated spread of the disease.
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is a Gram-positive bacterium, the spores of which are the causative agent of the most destructive brood disease of honeybees, American foulbrood (AFB). Obtaining viable spores of pathogen strains is requisite for different studies concerning AFB. The aim of this work was to investigate the effects of five saccharides that may naturally occur in higher amounts in bee larvae on in vitro sporulation of .

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Antibacterial activity is the most investigated biological property of honey. The goal of this study was to evaluate the antibacterial activity of 57 Slovak blossom honeys against and and investigate the role of several bioactive substances in antibacterial action of honeys. Inhibitory and bactericidal activities of honeys were studied to determine the minimum inhibitory and bactericidal concentrations.

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Article Synopsis
  • - Understanding the substrate specificity of Xyloglucan xyloglucosyl transferases (XETs) is crucial for redefining their role in plant cell wall metabolism, challenging the idea that they only interact with cellulose-xyloglucan networks.
  • - The study identifies TmXET6.3, an enzyme from Tropaeolum majus, and demonstrates its preference for certain oligosaccharides, outlining key amino acids that influence its substrate interactions.
  • - Variants of TmXET6.3 show differing transglycosylation activities, indicating potential for engineering enzymes with enhanced or altered functions in plant cell wall modification.
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