A Pilot Study on Using an Artificial Intelligence Algorithm to Identify Urolith Composition through Abdominal Radiographs in the Dog.

In small animal practice, patients often present with urinary lithiasis, and prediction of urolith composition is essential to determine the appropriate treatment. Through abdominal radiographs, the composition of mineral radiopaque uroliths can be determined by considering many different factors; this can be complex and, as such, tailor-made for the use of artificial intelligence (AI). The Minnesota Urolith Center partnered with Hill's Pet Nutrition to develop a deep learning AI algorithm (CALCurad) within a smartphone application called the MN Urolith Application that allows for the preliminary assessment of urolith composition.

Intratumoral injection of holmium-166 microspheres as neoadjuvant therapy of soft tissue sarcomas in dogs.

Introduction: Minimally invasive microbrachytherapy is in development to treat solid tumors by intratumoral injection of (radioactive) holmium-166 (Ho) microspheres (MS). A high local dose can be administered with minimal damage to surrounding tissue because of the short soft tissue penetration depth of Ho beta radiation. We aimed to prospectively evaluate the safety and efficacy of Ho microbrachytherapy in client-owned canine patients with soft tissue sarcomas (STS).

Retrospective study of 20 cats surgically treated for insulinoma.

Objective: To report the clinical signs, histopathology results, and prognostic factors for outcomes following excision for feline insulinoma (INS).

Study Design: Retrospective study.

Sample Population: Twenty client-owned cats.

Case Report: Radioactive Holmium-166 Microspheres for the Intratumoral Treatment of a Canine Pituitary Tumor.

In this case study, a client-owned dog with a large pituitary tumor was experimentally treated by intratumoral injection of radioactive holmium-166 microspheres (HoMS), named Ho microbrachytherapy. To our knowledge, this is the first intracranial intratumoral treatment through needle injection of radioactive microspheres. A 10-year-old Jack Russell Terrier was referred to the Clinic for Companion Animal Health (Faculty of Veterinary Medicine, Utrecht University, The Netherlands) with behavioral changes, restlessness, stiff gait, and compulsive circling.

Internal Tandem Duplication of Exon 8 of Is Associated With Longer Total Survival in Canine Cutaneous Mast Cell Tumors.

Canine cutaneous mast cell tumors (ccMCTs) have a highly variable biological behavior and accurate prognostication is essential for therapeutic intervention. Internal tandem duplications (ITD) of exon 11 are the most commonly detected mutation in ccMCTs and are associated with poor prognosis and increased cellular proliferation. The prognostic value of detecting mutations in other exons of has not been systematically examined.