Publications by authors named "J Kinn"
Article Synopsis
- Cancer treatment often involves chemotherapy, which can weaken the immune system, but combining it with immunotherapy shows promise for better survival rates if planned carefully.
- This study found that doxorubicin, a chemotherapy drug, boosts CD86 expression on B cells, leading to enhanced activation of CD4 T cells when exposed to superantigen, and this effect is blocked by a specific antibody.
- Additionally, B cells from urinary bladder cancer patients treated with doxorubicin showed increased CD86 expression, indicating a potential approach to improve the effectiveness of combining chemotherapy with immunotherapy through tailored treatment schedules.
Background: Stage is an important prognostic factor in renal tumours and dissemination to regional lymph nodes is associated with poor outcomes. Lymph nodes are routinely assessed by immunohistochemistry and microscopic evaluation, a time-consuming process where micrometastases might go undiagnosed. We evaluate an alternative method for detecting metastatic cells in sentinel nodes (SNs) by flow cytometry.
View Article and Find Full Text PDFMany military personnel returning from deployment experience increases in psychological symptoms, including post-traumatic stress disorder (PTSD), depression, and mood changes. Patient health diaries are commonly used for self-reporting over time away from the clinic. "T2 Mood Tracker" is an application ("app") for smartphones and other mobile devices that enables users to rate their moods, to self-monitor across time, and to report their emotional experiences to health providers.
View Article and Find Full Text PDFHealth-related technology, its relevance, and its availability are rapidly evolving. Technology offers great potential to minimize and/or mitigate barriers associated with achieving optimal health, performance, and readiness. In support of the U.
View Article and Find Full Text PDFLeveraging technology: creating and sustaining changes for health.
Telemed J E Health
September 2014
Objective: The rapid growth and evolution of health-related technology capabilities are driving an established presence in the marketplace and are opening up tremendous potential to minimize and/or mitigate barriers associated with achieving optimal health, performance, and readiness. This article summarizes technology-based strategies that promote healthy habits related to physical activity, nutrition, and sleep.
Materials And Methods: The Telemedicine and Advanced Technology Research Center convened a workshop titled "Leveraging Technology: Creating & Sustaining Changes for Health" (May 29-30, 2013, Fort Detrick, MD).