Significance of bizarre cells in cervical screening liquid-based cytology: A prospective study of 15 cases.

Objective: The aim of this study was to assess the significance of bizarre cells (cells of squamous origin with a superficial squamous cell-type cytoplasm and characterised by multinucleation that produces bizarre nuclear shapes) in liquid-based cytology (LBC) Papanicoaou (pap) smears with clinical and histological follow-up correlation.

Methods: Fifteen patients, all with LBC samples containing bizarre cells, were identified in routine ThinPrep LBC workload. HPV testing was performed in each case using residual LBC material.

[Pulmonary thromboembolism over a 25-year period in data from the Institute of Pathology of the P.J. Safarik Medical School in Kosice].

Based on a review of archival autopsy protocols an analysis of the frequency of pulmonary thrombembolism in consecutive autopsy material is presented. The study interval for the analysis was oriented to the period between the years 1949-2000. Our analysis has shown a gradual progression of incidence of pulmonary thrombembolism, as demonstrated in relative figures.

[Verification of identification of infectious agents by culture in routine gynecologic cytological screening].

The original Bethesda classification system for reporting cervical/vaginal cytologic diagnoses has claimed besides oncologic evaluation also a statement on the presence of infectious agents. Their diagnosis should be followed by appropriate treatment. Based upon the comparison of careful bacterioscopic study in a series of 175 routine cervical smears with the results of microbiological, virological and mycological examinations the following pathogens might be-according to the authors' opinion-diagnosed as highly possible and recommended for laboratory verification: cocci, Gardnerella vaginalis, Klebsiella, Acinetobacter, Morganella Morgani, Candida, Trichomonas vaginalis, Chlamydia trachomatis and human papilloma virus.