Impact of diagnostic testing on outcomes of children with rumination syndrome.

Objectives: Rumination syndrome (RS) is diagnosed based on clinical criteria with or without diagnostic testing showing characteristic findings on antroduodenal manometry (ADM), high-resolution esophageal manometry (HREM), and multichannel intraluminal impedance-pH testing (MII-pH). The objective of this study was to evaluate the correlation between diagnostic testing and clinical outcomes.

Methods: We conducted a retrospective review of children with RS evaluated at our institution.

Are the 2009 Institute of Medicine gestational weight gain recommendations applicable in a contemporary South-East Asian pregnancy cohort? Results of a prospective analysis.

Gestational Weight Gain (GWG) modulates pregnancy outcomes and long-term offspring metabolic health. The 2009 Institute of Medicine (IOM) GWG recommendations have largely been validated in Caucasian and mono-ethnic East Asian cohorts. Asians are at higher metabolic risk at a lower body mass index (BMI), and this has prompted the World Health Organization (WHO) to identify lower BMI cut-offs for risk evaluation amongst Asians.

Efficacy and safety of a whole lung lavage program for artificial stone silicosis.

Background: The incidence of silicosis has increased due to occupational silica exposure from artificial stone, with no treatments proven to halt or reverse the disease. Whole lung lavage (WLL) involves the instillation of fluid into the lungs to wash out silica particles and disease-causing inflammatory cells. This study aimed to determine the feasibility, safety, and possible benefit of WLL in patients with artificial stone silicosis.

Modelling the effects of intervention measures in reducing the risk of norovirus transmission in preschool settings.

Singapore has seen an increase in norovirus outbreaks in preschools from 2019 to 2022 primarily due to person-to-person transmission. This study describes the use of compartmental susceptible-exposed-infectious-recovered (SEIR) modelling to simulate the spread of norovirus among preschool children in a classroom setting. Different intervention measures, such as isolation of infected preschoolers, handwashing and surface decontamination were modelled to quantify their effectiveness at reducing the number of children infected.