Publications by authors named "J Kevin Wilkes"

Children with cancer or hematopoietic cell transplant (HCT) frequently require ICU care. We conducted a retrospective cohort study using Healthcare Cost and Utilization Project's State Inpatient Databases from 21 U.S.

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Article Synopsis
  • - The study highlights the limited impact of electronic health record (EHR) data on pediatric oncology research due to fewer pediatric cancer cases and challenges in identifying phenotypic cases within EHR data.
  • - ExtractEHR, a software package originally designed for reporting clinical trial adverse events, has been expanded to create comprehensive multisite EHR data sets for pediatric cancer research, enabling automated data extraction across hospitals.
  • - Installations of ExtractEHR have occurred at four major pediatric institutions, and it has been used for various research activities, including clinical epidemiology studies and multicenter trials, with ongoing efforts to enhance its capabilities for sustainability and interoperability.
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Introduction: Women with obesity are less likely to participate in mammographic screening and more likely to develop post-menopausal breast cancer. We describe the co-production of a novel training intervention for breast screening staff, targeting obesity-related barriers to participating in a population-based mammographic screening.

Methods: A Stakeholder Consultant Group (SCG) was established to guide the co-production process.

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Most epidemiological studies in pediatric heart failure (HF) use administrative database sources, defining patient cohorts by presence of a single HF ICD code. However, the ability of ICD codes to identify true HF patients is unknown in pediatrics. Here we describe the accuracy of HF ICD-10-CM code search algorithms, in identifying pediatric patients with HF from electronic data sources.

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Objective: To better delineate multiplexed gastrointestinal polymerase chain reaction (PCR) panel (MGPP) diagnostic and therapeutic stewardship for patients undergoing treatment for acute leukemia including indications and benefits of testing, optimal timing, and interpretation of results.

Study Design: We retrieved all MGPP ordered on 662 consecutive patients admitted with newly diagnosed acute leukemia between June 2015 and May 2024.

Setting: Regional referral center for acute leukemia.

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