Publications by authors named "J Keshri"

The present study investigated the indigenous metal-tolerant bacterial populations in the mine-water microbiome. Our intention was to assess the effects of the metal concentrations in mine water on the bacterial community of mine waters. The bacterial communities in Vanadium and Gold mine-water samples were exposed to different heavy-metal Arsenic, Cadmium, Chromium, Nickel, Mercury and Vanadium at two different concentrations (5 and 25 mM).

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In an attempt to isolate new probiotic bacteria, two Gram-variable, spore-forming, rod-shaped aerobic bacteria designated as strain A4 and A15 were isolated from the feces of Canada geese (). Strain A4 was able to grow in high salt levels and exhibited lipase activity, while A15 did not propagate under these conditions. Both were positive for starch hydrolysis, and they inhibited the growth of .

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In chickens, early life exposure to environmental microbes has long-lasting impacts on gastrointestinal (GI) microbiome development and host health and growth, via mechanisms that remain uncharacterized. In this study, we demonstrated that administrating a fecal microbiome transplant (FMT) from adults to day-of-hatch chicks results in significantly higher body mass of birds and decreased residual feed intake (RFI), implying enhanced feed efficiency, at 6 weeks of age. To assess the potential mechanisms through which FMT affects adult bird phenotype, we combined 16 S rRNA gene amplification, metagenomic, and comparative genomic approaches to survey the composition and predicted activities of the resident microbiome of various GI tract segments.

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Article Synopsis
  • - The concept of successional trajectories explains how small initial differences in community composition can lead to large variations in mature communities, particularly in the context of microbiomes in animals.
  • - In commercial poultry settings, chicks are isolated from adult birds, creating a different microbial community development trajectory compared to non-industrial environments where they encounter various microbes, yet the impacts of these differences are not well understood.
  • - The study involved transferring cecal material across generations of birds to assess microbial community stability, comparing the effects of host-selected cecal versus environmental inocula on the chicks’ gut microbiomes and health, revealing that the community structure changed significantly with cecal inoculation and impacted chick growth.
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Here, we present the draft genome sequences of two strains, HF117_J1_D and USDA818B3_A, isolated in Pomona, California, from the gastrointestinal (GI) tract of backyard and commercial broiler chickens, respectively. The draft genomes of both strains appear to represent novel species.

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